ABSTRACT
Se describe el caso clínico de una paciente con diagnóstico histológico de mastitis granulomatosa idiopática, enfermedad poco frecuente en la que se utilizan inmunosupresores como tratamiento descripto y puede confundirse con otras entidades atendidas en la especialidad. Se describe el caso y se realiza una revisión de la literatura.
The clinical case of a patient with a histological diagnosis of idiopathic granulomatous mastitis is described, a rare disease in which immunosuppressants are used as the described treatment and can be confused with other entities treated in the specialty. The case is described and a literature review is carried out.
Subject(s)
Humans , Female , Adult , Methotrexate/therapeutic use , Granulomatous Mastitis/diagnosis , Granulomatous Mastitis/drug therapy , Immunosuppressive Agents/therapeutic use , Granulomatous Mastitis/immunologyABSTRACT
INTRODUCTION: We used the immersion technique for the evaluation of duodenal mucosa for several years and we observed discordant results in relation to the literature. OBJECTIVE: To evaluate the immersion technique in the diagnosis of duodenal mucosa diseases. PATIENTS AND METHOD: We performed an upper endoscopy, immersion technique, chromoendoscopy and biopsies of the second portion of the duodenum to the patients who met the inclusion criteria. It was reported the presence of villi and the partial or total absence of them. RESULTS: The standard endoscopy showed absence of villi in 16 patients and normal mucosa in 384. The comparison between these results and those of the biopsies showed that biopsies were normal in 3 patients with presumed absence of villi and had a partial atrophy of villi in 1 patient with normal endoscopy. With the immersion technique and the chromoendoscopy we observed absence of villi in 13 patients and normal mucosa in 386. When we compared these results with those of the biopsies, we observed that 1 normal patient had a partial atrophy of villi. These results indicate that standard endoscopy has a sensitivity of 92
, a specificity of 99
, a positive predictive value of 81
and a negative predictive value of 99
. The immersion technique and chromoendoscopy have a sensitivity of 92
, a specificity of 100
, a positive predictive value of 100
and a negative predictive value of 99
. CONCLUSION: In our experience the immersion technique does not improve the visualization of the villi compared with the standard endoscopy and the chromoendoscopy.